The year is 1862, the twilight of the Tokugawa shogunate.

A young woman ventures into an unnamed city that has collapsed into chaos and disorder to search for her journalist brother.

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Set fifteen years in the then-future year 1983, the series tells the tale of the crew and passengers of a sub-orbital transport ship named Spindrift. In the pilot episode, the Spindrift is en route from Los Angeles to London, on an ultra-fast sub-orbital flight. Just beyond Earth's boundary with space, the Spindrift encounters a magnetic space storm, and is dragged through a space warp to a mysterious planet where everything is twelve times larger than on Earth, whose inhabitants the Earthlings nickname "the Giants". The Spindrift crash-lands, and the damage renders it inoperable.

"Genius" accidentally invents "goo" which causes living things to rapidly grow to an enormous size. Seeing an opportunity to get rich, some delinquent teenagers steal the "goo" and, as a result of a sophomoric dare, consume it themselves and become thirty feet tall. They then take over control of the town by kidnapping the sheriff's daughter and dancing suggestively.

In war-torn colonial America, in the midst of a bloody battle between British, the French and Native American allies, the aristocratic daughter of a British Colonel and her party are captured by a group of Huron warriors. Fortunately, a group of three Mohican trappers comes to their rescue.

Ron Ryan is accused of a murder he did not commit. As his family races to prove his innocence, he and a priest aim for redemption.

1926: While on tour promoting his latest movie "Son Of The Sheik", Rudolph Valentino, the Hollywood silent screen icon, suffers a sudden collapse and is hospitalized at the New York Polyclinic Hospital. After an emergency surgery, Valentino loses his grip on reality and, while hallucinating, reexperiences his life in Hollywood from - as a silent film shown at a movie palace, the magical portal between life and eternity, between reality and illusion. Dubbed "The Great Lover" around the world, Valentino plays dashing and virile Sheiks on the screen and drives his female audience into hysteria. However, his private life is a complete failure - the Sheik cannot satisfy even his own domineering wife. Snapping back to reality, Valentino finds himself abandoned, alone and stricken with illness. Pam, a young deaf-mute Valentino's fan, who works as a nurses' aid at the hospital, will show the God of Love for the first time in his life what love can truly mean.

A small-time Belfast thief, Gerry Conlon, is wrongly convicted of an IRA bombing in London, along with his father and friends, and spends 15 years in prison fighting to prove his innocence.

In the Valley of the Moon, follows a young man working as a hitman for the Italian mob in 1977. He takes a job in Petaluma, California, posing as a potential buyer at an open house to confront the realtor who he suspects has a sinister connection to his past.